91´óÏ㽶

protein structures and brain images

Biophysics Job Openings at the 91´óÏ㽶

We are seeking motivated, highly skilled, and creative individuals to join our team. Jobs openings in Biophysics are listed.

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Department Administrator - Biophysics

Position Description

Every great life-changing discovery begins the same way—with new knowledge. It can change everything, from a single life to the future of entire communities. That’s why academic medicine, and the continuous pursuit of knowledge, is at the center of everything we do at the 91´óÏ㽶 (MCW).

Purpose

In the role of Department Administrator in Biophysics, reporting to the Department Chair, you will direct the administrative and financial activities of a basic science department to include all financial, human and physical resources needed to carry out departmental goals effectively and efficiently. Function as the department’s agent and representative with internal and external entities.

Primary Functions

  • Responsible for the smooth function and development of department administrative operations to include information systems, contract development and negotiations, as well as, system design and development to support all department functions.
  • Develop annual budget. Monitor expenditures in relation to established budget, develop budget controls and reports, and analyze data against benchmarks.
  • In conjunction with Department Chair, develop and monitor strategic long- and short-term program and space planning including building design. Set priorities and goals.
  • Develop and monitor administrative infrastructure to support department operations to include staffing levels, compensation plan, organizational development, recruitment and retention, and team building.
  • Integrate and coordinate department activities with 91´óÏ㽶administration, internal and external entities. Negotiate contracts as required.
  • Develop and monitor systems for auditing and tracking financial matters. Monitors department compliance of operational policies and procedures. Work with department faculty regarding grant writing, adherence to budget guidelines, and opportunities for extramural funding.
  • In conjunction with Department Chair, develop and assess internal and external partnership opportunities.
  • Serve as advisor to chair on non-research issues including strategic planning, faculty hiring and disciplinary practices, faculty salary and institutional and inter-institutional negotiations.

Knowledge – Skills – Abilities

  • Possess excellent oral and written communication skills.
  • Set and communicate priorities, effectively planning and organizing the work of the group.
  • Possess strong critical thinking, problem solving and attentiveness to detail.
  • Apply education, training, and work experience to improve the performance of the organization.
  • Lead by setting an appropriate example.
  • Successfully manage stressful situations and change effectively.
  • Foster teamwork.
  • Clearly communicate information necessary for business success.
  • Delegates work effectively.
  • Maintain confidences.
  • Demonstrate personal integrity in all interactions.

Faculty Position in Structural and Chemical Biology

Position. The 91´óÏ㽶 (MCW) Cancer Center (CC) in partnership with basic science departments (Biochemistry, Biophysics, Pharmacology & Toxicology, Cell Biology, Neuroscience & Anatomy, Microbiology & Immunology) has made a strategic decision to expand on its strengths in Structural and Chemical Biology (SCB) and now invites applications for tenure-track positions at all levels.

This cluster recruitment seeks individuals to establish internationally leading research programs that apply the tools of structural biology to fundamental questions in cancer biology or cancer therapeutics. The ideal candidate will focus on cryo-EM (Single-particle Analysis (SPA) or in-situ cryo-ET) and SPA data science. 91´óÏ㽶is equipped with a state-of-the-art 200-keV cryo-EM with direct electron detector and energy filter capable of final data collection for sub-4Ã… structure determination. 91´óÏ㽶Cryo-EM researchers have expanded instrumentation opportunities through participation in a statewide Cryo-EM consortium that includes the University of Wisconsin-Madison’s Cryo-EM Research Center, which is within 60 miles from 91´óÏ㽶and currently houses five new cryo-EMs, including two Titan Krios.

Qualifications. Applicants must have a doctoral degree in structural biology, biochemistry, biophysics or related discipline, at least two years of postdoctoral training, a strong publication record investigating structural and functional properties of biomolecules of cancer therapeutic relevance, and potential to obtain cancer-related extramural funding. 91´óÏ㽶is intent on attracting, developing, and retaining a diverse workforce and faculty body that reflects the community we serve. We value diversity of backgrounds, experience, thought, and perspectives to advance excellence in science and medicine. 91´óÏ㽶is a welcoming campus community with a strong culture of collaboration, partnership, and engagement with our surrounding community.

To apply. Please submit the following components to www.mcw.edu/careers (requisition #31368):

  1. Cover letter
  2. Curriculum vitae
  3. Summary of research accomplishments (4-page maximum) and future research plans (4-page maximum)
  4. Names and contact information of four references

Postdoctoral Fellow (Mickevicius Lab)

Purpose
A postdoctoral fellowship position is open in the Department of Biophysics at the 91´óÏ㽶 focusing on magnetic resonance imaging (MRI) technology development. This project will be dedicated to the deep learning-driven design of MRI pulse sequences, image reconstruction algorithms, and the quantitative estimation of tissue parameters. These efforts contribute to a larger initiative aimed at enhancing the accuracy and reproducibility of quantitative MRI. The Center for Imaging Research at 91´óÏ㽶houses two cutting-edge GE Premier 3T MRI systems, which will play a significant role in the research. We are seeking a candidate who is eager to work in a team-oriented laboratory environment that emphasizes innovation. The role includes mentoring graduate students in research methodologies, engaging in scientific publication, and preparation of grant proposals.

Primary Functions
Supervise and independently execute studies related to the project described above, including performing experiments, analyzing data, and disseminating results through presenting at conferences and writing manuscripts.

Knowledge – Skills – Abilities
Ideal candidates will have experience expertise in one or more of the following:

  • MRI pulse sequence design (GE HealthCare EPIC Preferred)
  • Programming in Python and C/C++
  • Machine learning with PyTorch
  • Excellent writing skills, as evidenced by first author publications

Research Technologist I

Purpose
Under general supervision, provide support for department research through projects, maintenance and communication of data, and execution of laboratory experiments. Support research on the structure and dynamics and in vivo function of bacterial proteins identified as drug targets for the development of novel antibiotics.

Primary Functions

  • Carry out experimental designs for sponsored research projects and perform routine experiments.
  • Record and compile accurate records and communicate summaries of experimental results.
  • Assist with the evaluation, interpretation, and assessment of experimental data and quality control of assays.
  • Participate in meetings with principal investigator and research staff and evaluate/interpret the validity of data as needed.
  • Carry out assigned duties for ordering and maintaining supply of inventories.
  • Operate, calibrate, and perform routine maintenance on specialized equipment used in research.
  • Prepare media and buffers and perform routine laboratory maintenance.
  • Express and purify recombinant proteins from E. coli using column chromatography.
  • Label, concentrate, and prepare samples for EPR spectroscopy and other biophysical studies.
  • Operate specialized EPR spectroscopy instrumentation as trained.
  • Carry out in vivo growth assays.
  • Perform other scientific and administrative duties as assigned.

Knowledge – Skills – Abilities
Ability to meticulously carry out experiments as trained. Ability to accurately determine basic math and chemistry calculations, maintain records, and carry out experiments in a timely and organized manner. Ability to work independently with proper training. Attention to detail. Honesty. Integrity. Experience in growing bacterial cultures, making buffers and media, carrying out molecular biology and microbiology assays and purifying protein from bacteria will be highly beneficial.

Why Work for Biophysics?

The Department of Biophysics has been on the forefront of innovation since its inception, and is brimming with creativity. We have strong research programs in structural biology and biomedical imaging, including electron paramagnetic resonance (EPR), nuclear magnetic resonance (NMR), and magnetic resonance imaging (MRI). State-of-the-art research resources geared toward these programs—including laboratories for EPR, NMR, MRI, X-ray crystallography, cryo electron microscopy, mass spectrometry, biomolecular analysis, and high-performance computing—are available.

Why Work at MCW?

The 91´óÏ㽶 brings together the most inquisitive minds in science, medicine, education, and community engagement to advance biomedical knowledge and solve human health challenges. Our goal is to harness the power of academic medicine, where scientists, clinicians, and students actively collaborate with each other and the community, to find novel solutions to the challenges in health and society today. We ask the questions no one else is asking to fuel the continuous cycle of knowledge that’s shaping the future of translational research.

Why Work in Milwaukee?

Milwaukee is one of the Midwest’s best-kept secrets and a prime location for the 91´óÏ㽶’s main campus. Milwaukee has a rich cultural heritage and is recognized for its museums, art and music scenes, championship-winning sports teams, festivals, breweries, and historical architecture. The city has access to a multitude of beautiful parks, rivers, and lakes. Milwaukee's charming neighborhoods are known for their character, variety, and architecture, and offer a superb quality of life. Milwaukee is a city that’s growing and changing, and there’s energy in the air.