91΄σΟγ½Ά

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Astrid Stucke, MD

Astrid Stucke, MD

Professor

Contact Information

Biography

Dr. Stucke has been with the 91΄σΟγ½Ά since 1999. She received her Medical Doctorate from the University of Heidelberg, Germany, and began residency training in Anesthesiology. In 1999, she moved to Milwaukee for a postdoctoral fellowship in the Department of Anesthesiology where she joined the group of Dr. Edward Zuperku and Dr. Eckehard Stuth. The interest of the group lies in "Central Control of Breathing." An in vivo model using the anesthetized or decerebrate dog is used to perform extracellular recordings of single cells and drug ejection onto these cells as well as nuclear injections in the respiratory regions of the brainstem. So far, neurons in the preBötzinger Complex, the caudal ventral respiratory group and the hypoglossal motor nucleus have been investigated. This work has been supported by several NIH grants and VA merit grants. Dr. Stucke's focus has been on the effects of volatile anesthetics on neurotransmission in respiratory premotor neurons as well as the effects of clinically relevant opioid concentrations on these neurons.

In the last year Dr. Stucke has changed the direction of her research to the effects of hypoxia in immature mammals. The study uses neonatal and young rabbits and investigates the mechanisms of hypoxic ventilatory depression, and especially the effects of anesthesia on animals at different ages.

In the meantime, Dr. Stucke has completed her residency in Anesthesiology and a fellowship in Pediatric Anesthesia, both at the 91΄σΟγ½Ά. She is now a staff anesthesiologist at Children's Wisconsin and divides her time between the operating room and the research laboratory.

Publications

  • (Luedeke CM, Rudolph MI, Pulverenti TS, Azimaraghi O, Grimm AM, Jackson WM, Jaconia GD, Stucke AG, Nafiu OO, Karaye IM, Nichols JH, Chao JY, Houle TT, Eikermann M.) Br J Anaesth. 2024 Aug 05 PMID: 39107163 08/07/2024

  • (Malcolm NJ, Palkovic B, Sprague DJ, Calkins MM, Lanham JK, Halberstadt AL, Stucke AG, McCorvy JD.) iScience. 2023 Jul 21;26(7):107121 PMID: 37416459 PMCID: PMC10320493 07/07/2023

  • (Stucke AG, Levitt ES, Montandon G.) Front Physiol. 2023;14:1348910 PMID: 38179143 PMCID: PMC10766328 01/05/2024

  • (Palkovic B, Mustapic S, Saric I, Stuth EAE, Stucke AG, Zuperku EJ.) Front Physiol. 2023;14:1156076 PMID: 37362432 PMCID: PMC10285059 06/26/2023

  • (Voulgarelis S, Fathi F, Yu B, Palkovic B, Chatzizacharias NA, Allen KP, Stucke AG.) Pediatr Transplant. 2022 Jun;26(4):e14230 PMID: 35064720 SCOPUS ID: 2-s2.0-85123506404 01/23/2022

  • (Palkovic B, Malcom NJ, McCorvy JD, Langer TM, Callison JJ, Stuth EA, Zuperku EJ, Stucke AG.) FASEB J. 2022 May;36 Suppl 1 PMID: 35553696 SCOPUS ID: 2-s2.0-85130030561 05/14/2022

  • (Palkovic B, Cook-Snyder D, Callison JJ, Langer TM 3rd, Nugent R, Stuth EAE, Zuperku EJ, Stucke AG.) Respir Physiol Neurobiol. 2022 May;299:103855 PMID: 35124284 PMCID: PMC8897277 SCOPUS ID: 2-s2.0-85124754852 02/07/2022

  • (Zuperku EJ, Hopp FA, Stuth EAE, Stucke AG.) Respir Physiol Neurobiol. 2021 Nov;293:103715 PMID: 34126261 PMCID: PMC8418273 SCOPUS ID: 2-s2.0-85108097773 06/15/2021

  • (Palkovic B, Callison JJ, Marchenko V, Stuth EAE, Zuperku EJ, Stucke AG.) Anesthesiology. 2021 Oct 01;135(4):649-672 PMID: 34352068 PMCID: PMC8489159 SCOPUS ID: 2-s2.0-85115636053 08/06/2021

  • (Voulgarelis S, Fathi F, Stucke AG, Daley KD, Kim J, Zimmerman MA, Hong JC, Starkey N, Allen KP, Yu B.) J Biomed Opt. 2021 May;26(5) PMID: 34021537 PMCID: PMC8145982 SCOPUS ID: 2-s2.0-85106702253 05/23/2021

  • (Birmingham EE, Stucke AG, Diaz CD.) Paediatr Anaesth. 2021 Apr;31(4):419-428 PMID: 33644930 SCOPUS ID: 2-s2.0-85101807396 03/02/2021

  • (Voulgarelis S, Stucke A.) Saudi Journal of Anaesthesia. January-March 2021;15(1):56-58 SCOPUS ID: 2-s2.0-85099588930 01/01/2021